Altered gluteal (buttock) muscle activation is commonly associated with hamstring injuries. The gluteal and hamstring should work together to push the thigh backward when we accelerate during running, but often the gluteal muscles fail leading to overload of the hamstrings. This is frequently associated with sway back postures where the trunk is slightly backward of the pelvis. Specific exercises to correct gluteal activation and timing in conjunction with postural correction eliminate this as an underlying cause.
While the lumbar spine can be the primary cause of thigh pain it is also an underlying cause of recurrent hamstring injuries most probably due to chronic irritation of the sciatic nerve which runs from the low back into the back of the thigh.